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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST2
All Species:
27.27
Human Site:
S518
Identified Species:
42.86
UniProt:
O95251
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95251
NP_008998.1
611
70642
S518
L
S
D
L
G
L
I
S
Y
R
S
Y
W
K
E
Chimpanzee
Pan troglodytes
XP_511869
806
91579
S713
L
S
D
L
G
L
I
S
Y
R
S
Y
W
K
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548192
555
64081
R473
Y
W
K
E
V
L
L
R
Y
L
H
N
F
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5SVQ0
613
70623
S520
L
S
D
L
G
L
I
S
Y
R
S
Y
W
K
E
Rat
Rattus norvegicus
Q810T5
612
70496
S519
L
S
D
L
G
L
I
S
Y
R
S
Y
W
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026512
611
70527
S518
L
S
D
L
G
L
I
S
Y
R
S
Y
W
K
E
Frog
Xenopus laevis
NP_001079995
617
71123
S524
L
S
D
L
G
L
I
S
Y
R
S
Y
W
K
E
Zebra Danio
Brachydanio rerio
NP_997800
568
65560
L486
S
Y
W
K
E
V
L
L
R
Y
M
Y
N
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X4
541
61216
P459
E
I
F
I
S
Q
N
P
S
T
D
G
E
K
P
Honey Bee
Apis mellifera
XP_392324
916
101344
S816
L
S
D
L
G
L
I
S
Y
R
S
Y
W
K
D
Nematode Worm
Caenorhab. elegans
Q9TYU5
458
53125
G376
A
F
K
R
R
H
P
G
E
D
I
T
V
Q
D
Sea Urchin
Strong. purpuratus
XP_782361
504
58083
Q422
K
K
N
K
I
Y
C
Q
N
L
C
L
L
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXD7
445
51348
V363
Y
R
G
Y
W
T
R
V
L
L
E
I
L
K
K
Baker's Yeast
Sacchar. cerevisiae
Q08649
445
52594
E363
T
L
I
T
L
L
V
E
H
Q
K
E
I
T
I
Red Bread Mold
Neurospora crassa
Q7S9B6
506
58788
E424
D
I
L
L
G
Y
N
E
R
K
E
A
C
T
I
Conservation
Percent
Protein Identity:
100
75.8
N.A.
89.3
N.A.
99
99
N.A.
N.A.
97.8
93.1
76.4
N.A.
33.7
34
30.9
39.2
Protein Similarity:
100
75.8
N.A.
89.5
N.A.
99
99
N.A.
N.A.
98.5
95.9
83.4
N.A.
49.5
48.1
48.6
53.8
P-Site Identity:
100
100
N.A.
13.3
N.A.
100
100
N.A.
N.A.
100
100
6.6
N.A.
6.6
93.3
0
0
P-Site Similarity:
100
100
N.A.
33.3
N.A.
100
100
N.A.
N.A.
100
100
26.6
N.A.
13.3
100
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
31.9
31.2
Protein Similarity:
N.A.
N.A.
N.A.
50.4
47.6
47.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
7
0
7
0
0
% C
% Asp:
7
0
47
0
0
0
0
0
0
7
7
0
0
0
14
% D
% Glu:
7
0
0
7
7
0
0
14
7
0
14
7
7
0
40
% E
% Phe:
0
7
7
0
0
0
0
0
0
0
0
0
7
7
0
% F
% Gly:
0
0
7
0
54
0
0
7
0
0
0
7
0
0
7
% G
% His:
0
0
0
0
0
7
0
0
7
0
7
0
0
0
0
% H
% Ile:
0
14
7
7
7
0
47
0
0
0
7
7
7
0
14
% I
% Lys:
7
7
14
14
0
0
0
0
0
7
7
0
0
60
20
% K
% Leu:
47
7
7
54
7
60
14
7
7
20
0
7
14
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
14
0
7
0
0
7
7
0
0
% N
% Pro:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
7
0
7
0
7
0
0
0
14
0
% Q
% Arg:
0
7
0
7
7
0
7
7
14
47
0
0
0
0
0
% R
% Ser:
7
47
0
0
7
0
0
47
7
0
47
0
0
0
0
% S
% Thr:
7
0
0
7
0
7
0
0
0
7
0
7
0
14
0
% T
% Val:
0
0
0
0
7
7
7
7
0
0
0
0
7
0
0
% V
% Trp:
0
7
7
0
7
0
0
0
0
0
0
0
47
0
0
% W
% Tyr:
14
7
0
7
0
14
0
0
54
7
0
54
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _